郭岩
发布时间:2025-04-11


郭岩,副教授


研究方向:心脑血管药理学


电子邮箱:guoyanzx@126.com


教育经历:
(1) 2005/09-2008/06,维多利亚老品牌vic3308,药理学专业,博士

(2)2000/09-2003/06,维多利亚老品牌vic3308,药理学专业,硕士
(3)1995/09-2000/06, 中国医科大学,临床专业,学士


工作经历:

1.2011/05-2012/07,美国Oregon Health & Science University,访问学者

2.2008/10-至今,维多利亚老品牌vic3308,药理学教研室,副教授

3.2003/07-2008/10,维多利亚老品牌vic3308,药理学教研室,助教、讲师


发表论文情况:

1.Fang F, Sheng J, Guo Y, Wen J, Chen Z.Protection of H2S against Hypoxia/Reoxygenation Injury in Rat Hippocampal Neurons through Inhibiting Phosphorylation of ROCK2 at Thr436 and Ser575.Pharmaceuticals (Basel). 2023 Jan 31;16(2):218.

2.Yin X, Liu B, Ding Y, Li X, Sheng J, Guo Y, Chen Z, Wen J.Total flavones of Rhododendron induce the transformation of A1/A2 astrocytes via promoting the release of CBS-produced H2S. Phytomedicine. 2023 Mar;111:154666.

3.Xue M, Chen S, Xi J, Guan Q, Chen W, Guo Y, Chen Z.Protection against Hypoxia-Reoxygenation Injury of Hippocampal Neurons by H2S via Promoting Phosphorylation of ROCK2 at Tyr722 in Rat Model. Molecules. 2022 Jul 18;27(14):4567.

4.Zhang Y, Li K, Wang X, Ding Y, Ren Z, Fang J, Sun T, Guo Y, Chen Z, Wen J.CSE-Derived H2S Inhibits Reactive Astrocytes Proliferation and Promotes Neural Functional Recovery after Cerebral Ischemia/Reperfusion Injury in Mice Via Inhibition of RhoA/ROCK2 Pathway.ACS Chem Neurosci. 2021 Jul 21;12(14):2580-2590.

5.Guo Y,Yu X, Chen S, We J,Chen Z. Total flavones of Rhododendron simsii Planch flower protect rat hippocampal neuron from hypoxia-reoxygenation injury via activation of BKCa channel.J Pharm Pharmacol, 2020, 72(1):111-120.