许寒杨，助理实验师

研究方向：分子药理学

电子邮箱：2022510053@ahmu.edu.cn

办公室：基础楼409

教育经历：

(1)2019/9 - 2022/6，维多利亚老品牌vic3308，药理学，硕士

(2) 2015/9 - 2019/7，皖南医学院，药学，学士

工作经历：

2022/09-至今，维多利亚老品牌vic3308基础药理学教研室，助理实验师

发表论文情况：

1.Xu HY, Jiao YH, Li SY, Zhu X, Wang S, Zhang YY, Wei YJ, Shen YJ, Wang W, Shen YX, Shao JT. Hepatocyte-derived MANF mitigates ethanol-induced liver steatosis in mice via enhancing ASS1 activity and activating AMPK pathway. Acta Pharmacol Sin. 2023 Jan;44(1):157-168. doi: 10.1038/s41401-022-00920-8. Epub 2022 Jun 2. PMID: 35655095; PMCID: PMC9813016.

2. Shen QY, Wang D,Xu HY, Wei CS, Xiao XY, Liu J, Shen YJ, Fang L, Feng LJ, Shen YX. Mesencephalic astrocyte-derived neurotrophic factor attenuates acute lung injury via inhibiting macrophages' activation. Biomed Pharmacother. 2022 Jun;150:112943. doi: 10.1016/j.biopha.2022.112943. Epub 2022 Apr 8. PMID: 35405395.

3. Zhou H, Liu Y, Su Y, Ji P, Kong L, Sun R, Zhang D,Xu H, Li W, Li W. Ginsenoside Rg1 attenuates lipopolysaccharide-induced chronic liver damage by activating Nrf2 signaling and inhibiting inflammasomes in hepatic cells. J Ethnopharmacol. 2024 Apr 24;324:117794. doi: 10.1016/j.jep.2024.117794. Epub 2024 Jan 19. PMID: 38244950.

4. Jin N, Wu J, Ye S, Xue J, Meng T, Hu L, Jiang S,Xu H, Yu Y, Hu D, Zhang G. Injectable Dynamic ROS-Responsive COF-Modified Microalgae Gels for In Vivo bFGF Delivery to Treat Diabetic Wounds. ACS Appl Mater Interfaces. 2024 Apr 17;16(15):18608-18626. doi: 10.1021/acsami.4c01509. Epub 2024 Apr 2. PMID: 38565551.

5. Kong L, Liu Y, Li J, Wang Y, Ji P, Shi Q, Han M,Xu H, Li W, Li W. Ginsenoside Rg1 alleviates chronic inflammation-induced neuronal ferroptosis and cognitive impairments via regulation of AIM2 - Nrf2 signaling pathway. J Ethnopharmacol. 2024 Aug 10;330:118205. doi: 10.1016/j.jep.2024.118205. Epub 2024 Apr 17. PMID: 38641079.

6. Zhuang J, Zhang H, Wu J, Hu D, Meng T, Xue J,Xu H, Wang G, Wang H, Zhang G. Redox-Responsive AIEgen Diselenide-Covalent Organic Framework Composites Targeting Hepatic Macrophages for Treatment of Drug-induced Liver Injury. Small. 2024 Nov;20(47):e2402656. doi: 10.1002/smll.202402656. Epub 2024 Aug 14. PMID: 39140196.

7. Feng X, Wu B,Xu H, Chen C, Ye J. Virtual Screening and Biological Evaluation of Natural Products as Novel VPS34 Inhibitors that Modulate Autophagy. ChemMedChem. 2025 Mar 3;20(5):e202400580. doi: 10.1002/cmdc.202400580. Epub 2024 Dec 3. PMID: 39578246.

8. Li L, Zhou H, Li M, Liu W, Li Y, Xu H, Jiang J, Yang Y, Gong Y. Salvianolic acid B ameliorates hepatic fibrosis via inhibiting p300/CBP. Eur J Pharmacol. 2025 Mar 7;998:177495. doi: 10.1016/j.ejphar.2025.177495. Epub ahead of print. PMID: 40058756.

9. Shao J, Wang W, Li S, Yin G, Han L, Wang X, Cai M, Yang T, Wang Y, Qu W, Jiao Y, Wang P,Xu H, Zhu X, Ying S, Xu S, Sheng Q, Fang J, Jiang T, Wei C, Shen Y, Shen Y. Nuclear Overexpression of SAMHD1 Induces M Phase Stalling in Hepatoma Cells and Suppresses HCC Progression by Interacting with the Cohesin Complex. Adv Sci (Weinh). 2025 Feb;12(6):e2411988. doi: 10.1002/advs.202411988. Epub 2024 Dec 16. PMID: 39679869; PMCID: PMC11809348.

10. Liu Y, Fu Y, Wang G, Su Y, Sun R, Zhou H, Ji P,Xu H, Li W, Li W. Knockout of Trpc6 attenuates T2DM-induced liver injury and inflammation by inhibiting CN-NFAT2-NLRP3 signalling in mice. Pathol Res Pract. 2025 May;269:155894. doi: 10.1016/j.prp.2025.155894. Epub 2025 Mar 5. PMID: 40056751.